SHANK2
SH3 and multiple ankyrin repeat domains 2
Synonymes:
AUTS17, CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3
Espèce(s):
Human SHANK2 (22941), Mouse Shank2 (210274), Rat Shank2 (171093), sheep SHANK2 (101117805), domestic cat SHANK2 (101088878), Zebrafish shank2 (567595), cow SHANK2 (618649), Domestic Rabbit SHANK2 (100338286), naked mole-rat Shank2 (101704570), chicken SHANK2 (428858) ...Plus
ID UniProtKB:
ID du gène:
- Human(22941) Summary: This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(210274) SH3/ankyrin domain gene 2
- Rat(171093) SH3 and multiple ankyrin repeat domains 2
- sheep(101117805) SH3 and multiple ankyrin repeat domains 2
- domestic cat(101088878) SH3 and multiple ankyrin repeat domains 2
- Zebrafish(567595) SH3 and multiple ankyrin repeat domains 2
- cow(618649) SH3 and multiple ankyrin repeat domains 2
- Domestic Rabbit(100338286) SH3 and multiple ankyrin repeat domains 2
- naked mole-rat(101704570) SH3 and multiple ankyrin repeat domains 2
- chicken(428858) SH3 and multiple ankyrin repeat domains 2
- domestic guinea pig(100732196) SH3 and multiple ankyrin repeat domains 2
- dog(483677) SH3 and multiple ankyrin repeat domains 2
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-pan-Shank Antibody, clone N23B/49, clone N23B/49, from mouse,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-SHANK2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
western blot
western blot
Anti-SHANK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence