Accéder au contenu
MilliporeSigma

RGS1

regulator of G-protein signaling 1

Synonymes:
1R20, BL34, IER1, IR20
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5996) Summary: This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]
  • Mouse(50778) regulator of G-protein signaling 1
  • Rat(54289) regulator of G-protein signaling 1
  • domestic guinea pig(100715338) regulator of G-protein signaling 1
  • naked mole-rat(101701218) regulator of G-protein signaling 1
  • cow(540836) regulator of G-protein signaling 1
  • chicken(424360) regulator of G-protein signaling 1
  • Zebrafish(556179) regulator of G-protein signaling 1
  • Thale Cress(822207) putative membrane receptor protein RGS1
  • domestic cat(101088975) regulator of G-protein signaling 1
  • dog(488585) regulator of G-protein signaling 1
  • sheep(101122711) regulator of G-protein signaling 1
  • Horse(100034151) regulator of G-protein signaling 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-RGS1 antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
human, mouse
Application
western blot
Anti-RGS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-RGS1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-RGS1/1R20 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse
Application
ELISA
western blot

Proteins

Référence du produit
Description
Espèce(s)
RGS1, His tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Rgs1,
Espèce(s)
mouse