RBL1
retinoblastoma-like 1 (p107)
Synonymes:
CP107, PRB1, p107
Espèce(s):
Human RBL1 (5933), Mouse Rbl1 (19650), Rat Rbl1 (680111), Thale Cress RBL1 (817453), naked mole-rat Rbl1 (101707342), domestic guinea pig Rbl1 (100727381), Domestic Rabbit RBL1 (100342365), Zebrafish rbl1 (795522), cow RBL1 (524870), domestic cat RBL1 (101095164) ...Plus
ID UniProtKB:
ID du gène:
- Human(5933) Summary: The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(19650) retinoblastoma-like 1 (p107)
- Rat(680111) retinoblastoma-like 1 (p107)
- Thale Cress(817453) protein RHOMBOID-like 1
- naked mole-rat(101707342) retinoblastoma-like 1 (p107)
- domestic guinea pig(100727381) retinoblastoma-like 1 (p107)
- Domestic Rabbit(100342365) retinoblastoma-like 1 (p107)
- Zebrafish(795522) retinoblastoma-like 1 (p107)
- cow(524870) retinoblastoma-like 1 (p107)
- domestic cat(101095164) retinoblastoma-like 1 (p107)
- Horse(100069786) retinoblastoma-like 1 (p107)
- dog(477221) retinoblastoma-like 1 (p107)
- chicken(419126) retinoblastoma-like 1 (p107)
- sheep(101102328) retinoblastoma-like 1 (p107)
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-RBL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-RBL1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, horse, human, mouse, pig, rat
Application
western blot
Anti-RBL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-RBL1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
immunofluorescence
immunofluorescence
Monoclonal Anti-p107 antibody produced in mouse, clone KAB6, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse
Application
western blot