RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
Synonymes:
CALDAG-GEFI, CALDAG-GEFII, RASGRP, V, hRasGRP1
Espèce(s):
Human RASGRP1 (10125), Mouse Rasgrp1 (19419), Rat Rasgrp1 (29434), sheep RASGRP1 (101105504), domestic guinea pig Rasgrp1 (100735488), Domestic Rabbit RASGRP1 (100359319), Horse RASGRP1 (100071578), cow RASGRP1 (533125), chicken RASGRP1 (423290), domestic cat RASGRP1 (101093110) ...Plus
ID UniProtKB:
ID du gène:
- Human(10125) Summary: This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]
- Mouse(19419) RAS guanyl releasing protein 1
- Rat(29434) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- sheep(101105504) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- domestic guinea pig(100735488) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- Domestic Rabbit(100359319) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- Horse(100071578) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- cow(533125) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- chicken(423290) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- domestic cat(101093110) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- dog(478255) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- naked mole-rat(101699646) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-RASGRP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anticorps anti-RASGRP1, clone 10.1, clone 10.1, from mouse,
Espèces réactives
human
Application
western blot