PTPRC
protein tyrosine phosphatase, receptor type, C
Synonymes:
B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Espèce(s):
Human PTPRC (5788), Mouse Ptprc (19264), Rat Ptprc (24699), Zebrafish ptprc (559154), chicken PTPRC (386580), domestic cat PTPRC (101097123), Horse PTPRC (100061950), dog PTPRC (490255), sheep PTPRC (101102917), cow PTPRC (407152) ...Plus
ID UniProtKB:
ID du gène:
- Human(5788) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
- Mouse(19264) protein tyrosine phosphatase, receptor type, C
- Rat(24699) protein tyrosine phosphatase, receptor type, C
- Zebrafish(559154) protein tyrosine phosphatase, receptor type, C
- chicken(386580) protein tyrosine phosphatase, receptor type, C
- domestic cat(101097123) protein tyrosine phosphatase, receptor type, C
- Horse(100061950) protein tyrosine phosphatase, receptor type, C
- dog(490255) protein tyrosine phosphatase, receptor type, C
- sheep(101102917) protein tyrosine phosphatase, receptor type, C
- cow(407152) protein tyrosine phosphatase, receptor type, C
- Domestic Rabbit(100358807) protein tyrosine phosphatase, receptor type, C
- naked mole-rat(101710515) protein tyrosine phosphatase, receptor type, C
- domestic guinea pig(100730564) protein tyrosine phosphatase, receptor type, C
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-Mouse CD45 PerCP produced in mouse, ,
Espèces réactives
mouse
Application
flow cytometry
Monoclonal Anti-CD45 PerCP produced in mouse, ,
Espèces réactives
human
Application
flow cytometry
Monoclonal Anti-CD45 APC-Cyanine7 produced in mouse, ,
Espèces réactives
human
Application
flow cytometry
Anti-CD45.1 (Mouse), violetFluor® 450, clone A20 Antibody, clone A20, from mouse, violetFluor® 450,
Espèces réactives
mouse
Application
flow cytometry
CD45 (LCA) (2B11 & PD7/26) Mouse Monoclonal Antibody, ,
Espèces réactives
human
Application
immunohistochemistry
Small Molecule - Inhibitor
Proteins
Référence du produit
Description
Espèce(s)
CD45 Active human, recombinant, expressed in baculovirus infected insect cells, ≥90% (SDS-PAGE),
Espèce(s)
human
CD45 Protein, 10 µg, His6-tagged, recombinant, human CD45, amino acids 598-end, for use in Enzyme Assays.,
Espèce(s)
human
PTPRC (592-end), active, GST tagged from mouse, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
mouse