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PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

Synonymes:
LH2, TLH
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5352) Summary: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(26432) procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
  • Rat(300901) procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
  • dog(485702) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • domestic cat(101085741) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • naked mole-rat(101708679) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • domestic guinea pig(100735218) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • Zebrafish(100036767) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • sheep(101103613) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • chicken(424882) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • cow(533642) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • Horse(100061030) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PLOD2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, horse, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
Anti-PLOD2 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Plod2,
Espèce(s)
mouse
MISSION® esiRNA, targeting human PLOD2,
Espèce(s)
human