Accéder au contenu
MilliporeSigma

PCDHGA2

protocadherin gamma subfamily A, 2

Synonymes:
PCDH-GAMMA-A2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(56113) Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  • Mouse(93710) protocadherin gamma subfamily A, 2
  • Rat(498846) protocadherin gamma subfamily A, 2
  • chicken(431363) protocadherin gamma subfamily A, 2
  • sheep(101104993) protocadherin gamma subfamily A, 2
  • domestic cat(101097204) protocadherin gamma subfamily A, 2
  • cow(539654) protocadherin gamma subfamily A, 2
  • dog(607521) protocadherin gamma subfamily A, 2
  • naked mole-rat(101707494) protocadherin gamma subfamily A, 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-PCDHGA2 antibody produced in mouse, clone 2A7, ascites fluid,
Espèces réactives
human, mouse
Application
ELISA
western blot
Anti-PCDHGA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-PCDHGA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
western blot
Monoclonal Anti-PCDHGA2 antibody produced in mouse, clone 2A7, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
mouse
Application
ELISA
western blot