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NTRK1

neurotrophic tyrosine kinase, receptor, type 1

Synonymes:
MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4914) Summary: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
  • Mouse(18211) neurotrophic tyrosine kinase, receptor, type 1
  • Rat(59109) neurotrophic tyrosine kinase, receptor, type 1
  • chicken(396337) neurotrophic tyrosine kinase, receptor, type 1
  • domestic cat(101081603) neurotrophic tyrosine kinase, receptor, type 1
  • domestic guinea pig(100725325) neurotrophic tyrosine kinase, receptor, type 1
  • naked mole-rat(101724441) neurotrophic tyrosine kinase, receptor, type 1
  • cow(353111) neurotrophic tyrosine kinase, receptor, type 1
  • sheep(101109763) neurotrophic tyrosine kinase, receptor, type 1
  • Domestic Rabbit(100354292) neurotrophic tyrosine kinase, receptor, type 1
  • Horse(100064594) neurotrophic tyrosine kinase, receptor, type 1
  • dog(490404) neurotrophic tyrosine kinase, receptor, type 1
  • Zebrafish(30546) neurotrophic tyrosine kinase, receptor, type 1

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ELISA

Référence du produit
Description
Espèce(s)
Human TrkA ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anticorps anti-TrkA, Upstate®, from rabbit,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-TrkA Antibody, clone MNAC13, ,
Espèces réactives
human
Application
ELISA
neutralization
Anti-TrkA Antibody, clone 6B2, ascites fluid, clone 6B2, from mouse,
Espèces réactives
human, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-TrkA Antibody, clone 2J4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-phospho-TrkA (Tyr794) Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
K-252a, from Nonomuraea longicatena, ≥98% (HPLC),
Espèce(s)
rat, human
K-252a, Ready Made Solution, from Nonomuraea longicatena, >98%,
Espèce(s)
rat, human
Tyrphostin AG 879, 99% (HPLC),
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
TRKA (440-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human NTRK1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ntrk1,
Espèce(s)
mouse