MTA2
metastasis associated 1 family, member 2
Synonymes:
MTA1L1, PID
Espèce(s):
Human MTA2 (9219), Mouse Mta2 (23942), Rat Mta2 (361724), domestic guinea pig Mta2 (100732932), Zebrafish mta2 (326078), Domestic Rabbit MTA2 (100351042), Goat MTA2 (100861363), sheep MTA2 (101111404), cow MTA2 (515389), domestic cat MTA2 (101086925) ...Plus
ID UniProtKB:
ID du gène:
- Human(9219) Summary: This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011]
- Mouse(23942) metastasis-associated gene family, member 2
- Rat(361724) metastasis associated 1 family, member 2
- domestic guinea pig(100732932) metastasis associated 1 family, member 2
- Zebrafish(326078) metastasis associated 1 family, member 2
- Domestic Rabbit(100351042) metastasis associated 1 family, member 2
- Goat(100861363) metastasis associated 1 family, member 2
- sheep(101111404) metastasis associated 1 family, member 2
- cow(515389) metastasis associated 1 family, member 2
- domestic cat(101086925) metastasis associated 1 family, member 2
- Horse(100063490) metastasis associated 1 family, member 2
- dog(476057) metastasis associated 1 family, member 2
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-MTA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MTA2, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-MTA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
western blot
western blot
Anti- MTA2 antibody produced in rabbit, ,
Espèces réactives
human, rat
Application
immunohistochemistry
western blot
western blot