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MMP2

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

Synonymes:
CLG4, CLG4A, MMP-II, MONA, TBE-1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4313) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17390) matrix metallopeptidase 2
  • Rat(81686) matrix metallopeptidase 2
  • naked mole-rat(101696977) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • cow(282872) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • sheep(443115) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • chicken(386583) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic guinea pig(100719361) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • dog(403733) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Zebrafish(337179) matrix metalloproteinase 2
  • Horse(100033948) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Domestic Rabbit(100009000) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic cat(101098838) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • fruit fly(35997) Matrix metalloproteinase 2

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ELISA

Référence du produit
Description
Espèce(s)
Human MMP-2 ELISA Kit, for serum, plasma, cell culture supernatant,
Espèce(s)
human
Mouse MMP-2 ELISA Kit, for serum, plasma and cell culture supernatant,
Espèce(s)
mouse
Rat MMP-2 ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
rat

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-MMP-2 Antibody, a.a. 468-483 hMMP2, clone 42-5D11, clone 42-5D11, Chemicon®, from mouse,
Espèces réactives
bovine, horse, human, mouse, pig, rabbit, rat
Application
ELISA
immunohistochemistry

western blot
Anti-MMP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-MMP-2 (Ab-3) Mouse mAb (42-5D11), liquid, clone 42-5D11, Calbiochem®,
Espèces réactives
bovine, human, mouse, rat
Application
Anti-MMP-2 Antibody, pro and active form, clone VB3, clone VB3, Chemicon®, from mouse,
Espèces réactives
human
Application
ELISA
immunofluorescence

western blot
Anti- MMP2 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Marimastat, ≥98% (HPLC),
Espèce(s)
human, rat, mouse
CP-101537, ≥98% (HPLC),
Espèce(s)
human, rat, mouse
CP-471474, ≥98% (HPLC),
Espèce(s)
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Espèce(s)
human, rat, mouse

Proteins

Référence du produit
Description
Espèce(s)
MMP-2 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espèce(s)
human
Matrix Metalloproteinase-2 human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Espèce(s)
human
Matrix Metalloproteinase-2 from mouse, recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
mouse, rat

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Mmp2,
Espèce(s)
mouse
MISSION® esiRNA, targeting human MMP2,
Espèce(s)
human