MAP2K6
mitogen-activated protein kinase kinase 6
Synonymes:
MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3
Espèce(s):
Human MAP2K6 (5608), Mouse Map2k6 (26399), Rat Map2k6 (114495), dog MAP2K6 (480454), chicken MAP2K6 (417445), Zebrafish map2k6 (65239), domestic guinea pig Map2k6 (100731419), naked mole-rat Map2k6 (101703028), sheep MAP2K6 (101115047), Domestic Rabbit MAP2K6 (100355230) ...Plus
ID UniProtKB:
ID du gène:
- Human(5608) Summary: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]
- Mouse(26399) mitogen-activated protein kinase kinase 6
- Rat(114495) mitogen-activated protein kinase kinase 6
- dog(480454) mitogen-activated protein kinase kinase 6
- chicken(417445) mitogen-activated protein kinase kinase 6
- Zebrafish(65239) mitogen-activated protein kinase kinase 6
- domestic guinea pig(100731419) mitogen-activated protein kinase kinase 6
- naked mole-rat(101703028) mitogen-activated protein kinase kinase 6
- sheep(101115047) mitogen-activated protein kinase kinase 6
- Domestic Rabbit(100355230) mitogen-activated protein kinase kinase 6
- cow(286883) mitogen-activated protein kinase kinase 6
- domestic cat(101089813) mitogen-activated protein kinase kinase 6
- Horse(100053056) mitogen-activated protein kinase kinase 6
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-MAP2K6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-MAP2K6 antibody produced in mouse, clone 2F2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Anti-MKK6 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MAP2K6 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Référence du produit
Description
Espèce(s)
Proteins
Référence du produit
Description
Espèce(s)
MKK6 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE),
Espèce(s)
human
MKK6/SKK3 Protein, active, 10 µg, Active, N-terminal, maltose binding protein tagged, human MKK6/SKK3 fusion protein, amino acids 4-end. For use in Kinase Assays.,
Espèce(s)
human
MKK6/SKK3, active human, ≥80% (SDS-PAGE), recombinant, expressed in E. coli, Maltose binding protein tagged, buffered aqueous solution,
Espèce(s)
human
MKK6/SKK3 (S599D, T603D) Protein, active, 10 µg, Active, N-terminal MBP tagged, recombinant, human MKK6/SKK3 residues 4-end containing S599D & T603D mutations. For use in Kinase Assays.,
Espèce(s)
human
MKK6/SKK3 Protein, inactive, 50 g, Unactive, recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag, for use in Kinase Assays.,
Espèce(s)
human
esiRNA
Référence du produit
Description
Espèce(s)