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KREMEN2

kringle containing transmembrane protein 2

Synonymes:
KRM2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(79412) Summary: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
  • Mouse(73016) kringle containing transmembrane protein 2
  • Rat(287102) kringle containing transmembrane protein 2
  • naked mole-rat(101720049) kringle containing transmembrane protein 2
  • domestic cat(101098677) kringle containing transmembrane protein 2
  • sheep(101119273) kringle containing transmembrane protein 2
  • domestic guinea pig(100734476) kringle containing transmembrane protein 2
  • cow(618527) kringle containing transmembrane protein 2
  • dog(610753) kringle containing transmembrane protein 2

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ELISA

Référence du produit
Description
Espèce(s)
Human Kremen-2 ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-KREMEN2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-KREMEN2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse
Application
ELISA
immunocytochemistry

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Kremen2,
Espèce(s)
mouse