Accéder au contenu
MilliporeSigma

KLK3

kallikrein-related peptidase 3

Synonymes:
APS, KLK2A1, PSA, hK3
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(354) Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human PSA-total ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human
Human KLK3 / Prostate-specific Antigen ELISA Kit, ,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-Prostate-specific Antigen antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunohistochemistry

western blot
PSA (ER-PR8) Mouse Monoclonal Antibody, ,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-PSA antibody produced in mouse, clone A67-B/E3,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-KLK3 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-PSA Antibody, clone 1E10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot

Proteins

Numéro du produit
Description
Espèce(s)
Prostate Specific Antigen from human semen, buffered aqueous solution,
Espèce(s)
human
Prostate Specific Antigen from human semen, buffered aqueous solution,
Espèce(s)
human
Kallikrein-3 human, recombinant, expressed in human cells, ≥95% (SDS-PAGE),
Espèce(s)
human
Prostate Specific Antigen–α1-Antichymotrypsin Complex human, ≥99% (SDS-PAGE), buffered aqueous solution,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human KLK3,
Espèce(s)
human