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HSD3B2

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

Synonymes:
HSD3B, HSDB, SDR11E2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3284) Summary: The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
  • Mouse(15493) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
  • dog(483146) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
  • chicken(396015) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-HSD3B2 Antibody, clone 6, clone 6, from mouse,
Espèces réactives
human
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-HSD3B2 antibody produced in mouse, clone 1E8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-HSD3B2, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
Trilostane, ≥98% (HPLC),
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human HSD3B2,
Espèce(s)
human