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Merck

HRH3

histamine receptor H3

Synonymes:
GPCR97, HH3R
Espèce(s):
Human HRH3 (11255), Mouse Hrh3 (99296), Rat Hrh3 (85268), sheep HRH3 (101121700), Domestic Rabbit HRH3 (100009035), chicken HRH3 (428147), dog HRH3 (477282), domestic cat HRH3 (101084437), cow HRH3 (789851), Zebrafish hrh3 (561773)
ID UniProtKB:
Q9Y5N1, Q4QRI7, Q9GZX2, Q9H4K8
ID du gène:
  • Human(11255) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008]
  • Mouse(99296) histamine receptor H3
  • Rat(85268) histamine receptor H3
  • sheep(101121700) histamine receptor H3
  • Domestic Rabbit(100009035) histamine receptor H3
  • chicken(428147) histamine receptor H3
  • dog(477282) histamine receptor H3
  • domestic cat(101084437) histamine receptor H3
  • cow(789851) histamine receptor H3
  • Zebrafish(561773) histamine receptor H3
  • domestic guinea pig(100135541) histamine receptor H3

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
H128
(R)(−)-α-Methylhistamine dihydrochloride, solid, ≥98% (HPLC),
Espèce(s)
human
I135
Imetit dihydrobromide, ≥98% (HPLC),
Espèce(s)
human
B4638
Betahistine dihydrochloride, ≥98%,
Espèce(s)
human
M28804
2-(2-Methylaminoethyl)pyridine, 97%,
Espèce(s)
human
1065618
Betahistine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
T123
Thioperamide maleate salt, solid,
Espèce(s)
human
B4638
Betahistine dihydrochloride, ≥98%,
Espèce(s)
human
M28804
2-(2-Methylaminoethyl)pyridine, 97%,
Espèce(s)
human
1065618
Betahistine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
PHR2097
Betahistine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
SAB5701457
Anti-HRH3 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
H7125
Histamine, ≥97.0%,
Espèce(s)
human, rat

Small Molecule - Metabolite

Référence du produit
Description
Espèce(s)
M4910
1-Methylhistamine dihydrochloride, ≥98% (TLC), powder,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EHU141391
MISSION® esiRNA, targeting human HRH3,
Espèce(s)
human