HRAS
Harvey rat sarcoma viral oncogene homolog
Synonymes:
C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
Espèce(s):
Human HRAS (3265), Rat Hras (293621), dog HRAS (403735), cow HRAS (100298939), naked mole-rat Hras (101716053), chicken HRAS (396229), domestic guinea pig Hras (100735038), sheep HRAS (101104357)
ID UniProtKB:
ID du gène:
- Human(3265) Summary: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
- Rat(293621) Harvey rat sarcoma virus oncogene
- dog(403735) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- cow(100298939) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- naked mole-rat(101716053) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- chicken(396229) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- domestic guinea pig(100735038) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- sheep(101104357) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
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Small Molecule - Antagonist
Référence du produit
Description
Espèce(s)
Guanosine 5′-triphosphate sodium salt solution, HPLC purified, aqueous solution for RNA polymerase transcription,
Espèce(s)
human
Antibodies
Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-HRAS antibody produced in mouse, clone H-RAS-03,
Espèces réactives
human
Application
western blot
Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1), liquid, clone F235-1.7.1, Calbiochem®,
Espèces réactives
human, mouse, rat
Application
Anti-H-Ras Antibody, clone 3B13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
ELISA
affinity binding assay
western blot
affinity binding assay
western blot
Anticorps monoclonal de lapin anti-Ha-Ras, clone MC57, culture supernatant, clone MC57, from rabbit,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-HRAS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
esiRNA
Référence du produit
Description
Espèce(s)