HAP1
huntingtin-associated protein 1
Synonymes:
HAP2, HIP5, HLP, hHLP1
Espèce(s):
Human HAP1 (9001), Mouse Hap1 (15114), Rat Hap1 (29430), dog HAP1 (607751), cow HAP1 (618422), sheep HAP1 (101108406), domestic cat HAP1 (101088631)
ID UniProtKB:
ID du gène:
- Human(9001) Summary: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(15114) huntingtin-associated protein 1
- Rat(29430) huntingtin-associated protein 1
- dog(607751) huntingtin-associated protein 1
- cow(618422) huntingtin-associated protein 1
- sheep(101108406) huntingtin-associated protein 1
- domestic cat(101088631) huntingtin-associated protein 1
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-HAP1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-HAP1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-APE/Ref-1 Antibody, clone 13B8E5C2, clone 13B8E5C2, from mouse,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-HAP1 Antibody, clone 1B6, clone 1B6, from mouse,
Espèces réactives
mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-HAP1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
western blot