GLA
galactosidase, alpha
- Human(2717) Summary: This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq, Jul 2008]
- Mouse(11605) galactosidase, alpha
- Rat(363494) galactosidase, alpha
- chicken(422188) galactosidase, alpha
- Zebrafish(450083) galactosidase, alpha
- dog(480988) galactosidase, alpha
- domestic cat(101091428) galactosidase, alpha
- Horse(100060370) galactosidase, alpha
- cow(532742) galactosidase, alpha
- Goat(100861188) galactosidase, alpha
- Domestic Rabbit(100344610) galactosidase, alpha
- sheep(101106236) galactosidase, alpha
- domestic guinea pig(100718405) galactosidase, alpha
- naked mole-rat(101713601) galactosidase, alpha
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