GHSR
growth hormone secretagogue receptor
Human GHSR (2693), Mouse Ghsr (208188), Rat Ghsr (84022), dog GHSR (100101479), chicken GHSR (378911), domestic cat GHSR (101083540), cow GHSR (514203), Goat GHSR (100860920), naked mole-rat Ghsr (101702096), domestic guinea pig Ghsr (100731433)
- Human(2693) Summary: This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.[provided by RefSeq, Apr 2010]
- Mouse(208188) growth hormone secretagogue receptor
- Rat(84022) growth hormone secretagogue receptor
- dog(100101479) growth hormone secretagogue receptor
- chicken(378911) growth hormone secretagogue receptor
- domestic cat(101083540) growth hormone secretagogue receptor
- cow(514203) growth hormone secretagogue receptor
- Goat(100860920) growth hormone secretagogue receptor
- naked mole-rat(101702096) growth hormone secretagogue receptor
- domestic guinea pig(100731433) growth hormone secretagogue receptor
- sheep(443238) growth hormone secretagogue receptor
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Small Molecule - Inhibitor
[D-Trp7, Ala8, D-Phe10]-α-Melanocyte Stimulating Hormone Amide Fragment 6-11, ≥97% (HPLC),
rat, human