FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Synonymes:
CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3
Espèce(s):
Human FCGR3A (2214), Rat Fcgr3a (304966), dog FCGR3A (478984), sheep FCGR3A (100192433), cow FCGR3A (281766)
ID UniProtKB:
ID du gène:
- Human(2214) Summary: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Rat(304966) Fc fragment of IgG, low affinity IIIa, receptor
- dog(478984) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
- sheep(100192433) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
- cow(281766) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
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Antibodies
Référence du produit
Description
Espèces réactives
Application
CD16 (SP175) Rabbit Monoclonal Antibody, ,
Espèces réactives
human
Application
immunohistochemistry
Anti-FCGR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-CD16 antibody produced in mouse, clone MEM-154, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
flow cytometry
Anti-CD16A antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP189, affinity isolated antibody,
Espèces réactives
human
Application
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CD16a Antibody, clone 1E6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
esiRNA
Référence du produit
Description
Espèce(s)