ELAVL1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
Synonymes:
ELAV1, HUR, Hua, MelG
Espèce(s):
Human ELAVL1 (1994), Mouse Elavl1 (15568), Rat Elavl1 (363854), Domestic Rabbit ELAVL1 (100353220), Horse ELAVL1 (100060819), Zebrafish elavl1 (30736), dog ELAVL1 (611201), naked mole-rat Elavl1 (101713794), domestic cat ELAVL1 (101094402), domestic guinea pig Elavl1 (100735972) ...Plus
ID UniProtKB:
ID du gène:
- Human(1994) Summary: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]
- Mouse(15568) ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
- Rat(363854) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
- Domestic Rabbit(100353220) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
- Horse(100060819) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
- Zebrafish(30736) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
- dog(611201) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
- naked mole-rat(101713794) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
- domestic cat(101094402) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
- domestic guinea pig(100735972) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
- sheep(100307040) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
- chicken(395637) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
- cow(617316) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
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Antibodies
Référence du produit
Description
Espèces réactives
Application
RIPAb+ HuR - RIP Validated Antibody and Primer Set, from rabbit,
Espèces réactives
human, mouse, rat
Application
RIP
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-phospho HuR (Ser221) Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
xenopus, bovine, chicken, human, mouse, porcine
Application
inhibition assay
western blot
western blot
Anticorps anti-HuR, Upstate®, from rabbit,
Espèces réactives
human, mouse
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-HuR/ELAVL1 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-ELAVL1 antibody produced in mouse, clone 4G8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
esiRNA
Référence du produit
Description
Espèce(s)