DEFA1
defensin, alpha 1
Synonymes:
DEF1, DEFA2, HNP-1, HP-1, HP1, MRS
Espèce(s):
ID UniProtKB:
ID du gène:
- Human(1667) Summary: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, May 2010]
- Mouse(13216) defensin, alpha 1
- Horse(100307002) defensin, alpha 1
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Antibodies
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Description
Espèces réactives
Application
Anti-DEFA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-DEFA1, from rabbit, purified by affinity chromatography,
Espèces réactives
human, rhesus macaque
Application
flow cytometry
western blot
western blot
Proteins
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Description
Espèce(s)