CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
Synonymes:
CPC8, CYPIIC8, MP-12/MP-20
Espèce(s):
ID UniProtKB:
ID du gène:
- Human(1558) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-CYP2C8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-CYP2C8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-Cytochrome P450 2C8 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
western blot
western blot
Anti-CYP2C8 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Référence du produit
Description
Espèce(s)