CTSB
cathepsin B
Synonymes:
APPS, CPSB
Espèce(s):
Human CTSB (1508), Mouse Ctsb (13030), Rat Ctsb (64529), domestic guinea pig Ctsb (100714169), naked mole-rat Ctsb (101709008), dog CTSB (486077), Horse CTSB (100060963), domestic cat CTSB (101084873), cow CTSB (281105), sheep CTSB (780470)
ID UniProtKB:
ID du gène:
- Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(13030) cathepsin B
- Rat(64529) cathepsin B
- domestic guinea pig(100714169) cathepsin B
- naked mole-rat(101709008) cathepsin B
- dog(486077) cathepsin B
- Horse(100060963) cathepsin B
- domestic cat(101084873) cathepsin B
- cow(281105) cathepsin B
- sheep(780470) cathepsin B
- chicken(396329) cathepsin B
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Cathepsin B (Ab-1) Mouse mAb (CA10), lyophilized, clone CA10, Calbiochem®,
Espèces réactives
bovine, human, porcine
Application
Anti-Cathepsin B Antibody, clone 6I5D7, Rabbit Monoclonal, ,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Monoclonal Anti- Cathepsin B antibody produced in mouse, clone CB59-4B11, purified from hybridoma cell culture,
Espèces réactives
human, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Référence du produit
Description
Espèce(s)
Cathepsin B from human liver, buffered aqueous solution, ≥1,500 units/mg protein (E1%/280),
Espèce(s)
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Espèce(s)
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Espèce(s)
human
esiRNA
Small Molecule - Substrate
Référence du produit
Description
Espèce(s)