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CSTB

cystatin B (stefin B)

Synonymes:
CST6, EPM1, EPM1A, PME, STFB, ULD
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1476) Summary: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). [provided by RefSeq, Jul 2008]
  • Mouse(13014) cystatin B
  • Rat(25308) cystatin B (stefin B)
  • domestic guinea pig(100719016) cystatin B (stefin B)
  • naked mole-rat(101699171) cystatin B (stefin B)
  • cow(514170) cystatin B (stefin B)
  • cow(512805) cystatin B (stefin B)
  • dog(478424) cystatin B (stefin B)
  • chicken(418267) cystatin B (stefin B)
  • sheep(101123265) cystatin B (stefin B)

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ELISA

Référence du produit
Description
Espèce(s)
Human Cystatin B ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CSTB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CSTB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-CSTB antibody produced in mouse, clone M1-C1, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot

Proteins

Référence du produit
Description
Espèce(s)
Cystatin B human, recombinant, expressed in E. coli,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CSTB,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Cstb,
Espèce(s)
mouse