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Merck

CHD8

chromodomain helicase DNA binding protein 8

Synonymes:
AUTS18, HELSNF1
Espèce(s):
Human CHD8 (57680), Mouse Chd8 (67772), Rat Chd8 (65027), Zebrafish chd8 (568214), dog CHD8 (475401), domestic cat CHD8 (101097402), cow CHD8 (507111), Horse CHD8 (100059337), sheep CHD8 (101109181), domestic guinea pig Chd8 (100713580)
ID UniProtKB:
Q9HCK8, Q4G0D8, Q68DQ0, Q6DKH9, Q6P440, Q6ZNL7, Q8N3Z9, Q8NCY4
ID du gène:
  • Human(57680) Summary: This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
  • Mouse(67772) chromodomain helicase DNA binding protein 8
  • Rat(65027) chromodomain helicase DNA binding protein 8
  • Zebrafish(568214) chromodomain helicase DNA binding protein 8
  • dog(475401) chromodomain helicase DNA binding protein 8
  • domestic cat(101097402) chromodomain helicase DNA binding protein 8
  • cow(507111) chromodomain helicase DNA binding protein 8
  • Horse(100059337) chromodomain helicase DNA binding protein 8
  • sheep(101109181) chromodomain helicase DNA binding protein 8
  • domestic guinea pig(100713580) chromodomain helicase DNA binding protein 8
  • naked mole-rat(101698950) chromodomain helicase DNA binding protein 8

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Antibodies

Référence du produit
Description
Espèces réactives
Application
ZRB1885
Anti-CHD-8 Antibody, clone 1H9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey, mouse
Application
affinity binding assay
immunohistochemistry
western blot
HPA052186
Anti-CHD8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
MABN2648
Anti-CHD-8L Antibody, clone 1C10-1, ,
Espèces réactives
human, mouse
Application
immunoprecipitation (IP)
western blot
MABN2265
Anti-CHD-8 Antibody, clone 7F4.1, clone 7F4.1, from mouse,
Espèces réactives
human
Application
immunohistochemistry
western blot
HPA076133
Anti-CHD8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
western blot

esiRNA

Référence du produit
Description
Espèce(s)
EHU144761
MISSION® esiRNA, targeting human CHD8,
Espèce(s)
human