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Merck

CHAT

choline O-acetyltransferase

Synonymes:
CHOACTASE, CMS1A, CMS1A2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1103) Summary: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]
  • Mouse(12647) choline acetyltransferase
  • Rat(290567) choline O-acetyltransferase
  • sheep(101117817) choline O-acetyltransferase
  • domestic guinea pig(100718930) choline O-acetyltransferase
  • naked mole-rat(101711939) choline O-acetyltransferase
  • Thale Cress(821249) acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase
  • cow(524732) choline O-acetyltransferase
  • domestic cat(751512) choline O-acetyltransferase
  • Zebrafish(100170938) choline acetyltransferase
  • chicken(395314) choline O-acetyltransferase
  • dog(486775) choline O-acetyltransferase

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Choline Acetyltransferase (ChAT) Antibody, clone 2K16, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-CHAT antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL3173, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-CHAT antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL3169, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
Anti-CHAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse
Application
immunohistochemistry
Anti-Choline Acetyltransferase Antibody, Chemicon®, from chicken,
Espèces réactives
mouse
Application
immunocytochemistry
immunohistochemistry

Small Molecule - Cofactor

Référence du produit
Description
Espèce(s)
Acétyl-coenzyme A trisodium salt, ≥93% (HPLC), powder,
Espèce(s)
human, mouse, rat
Acétyl-coenzyme A lithium salt, ≥93% (HPLC),
Espèce(s)
human, mouse, rat

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Chat,
Espèce(s)
mouse