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CDC25B

cell division cycle 25B

Synonymes:
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(994) Summary: CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]
  • Mouse(12531) cell division cycle 25B
  • Rat(171103) cell division cycle 25B
  • domestic guinea pig(100716851) cell division cycle 25B
  • naked mole-rat(101701077) cell division cycle 25B
  • cow(505847) cell division cycle 25 homolog B (S. pombe)
  • dog(485790) cell division cycle 25 homolog B (S. pombe)
  • Horse(100052425) cell division cycle 25 homolog B (S. pombe)
  • domestic cat(101092757) cell division cycle 25 homolog B (S. pombe)
  • sheep(101120511) cell division cycle 25 homolog B (S. pombe)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CDC25B antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-CDC25B (pSer353) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-CDC25B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-CDC25B antibody produced in mouse, clone 7E8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-phospho-Cdc25b (pSer149) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
mouse
Application
western blot

Cell Lines

Référence du produit
Description
Espèce(s)
MCF10A CELLS CDC25B (-/-), ,
Espèce(s)
human

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
NSC 95397, ≥97% (HPLC),
Espèce(s)
human
NSC 663284, ≥98% (HPLC), solid,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CDC25B,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Cdc25b,
Espèce(s)
mouse