Accéder au contenu
MilliporeSigma

BRD2

bromodomain containing 2

Synonymes:
D6S113E, FSH, FSRG1, NAT, RING3, RNF3
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6046) Summary: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(14312) bromodomain containing 2
  • Rat(294276) bromodomain containing 2
  • domestic guinea pig(100734555) bromodomain containing 2
  • cow(505358) bromodomain containing 2
  • Domestic Rabbit(100343906) bromodomain containing 2
  • domestic cat(101084362) bromodomain containing 2
  • sheep(101110276) bromodomain containing 2
  • chicken(417049) bromodomain containing 2
  • dog(474868) bromodomain containing 2
  • naked mole-rat(101699681) bromodomain containing 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-BRD2 antibody produced in mouse, clone 3D10, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-BRD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-BRD2 Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human, rat
Application
immunohistochemistry
western blot
Goat anti-BRD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Espèces réactives
human
Application
western blot
Rabbit anti-BRD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Espèces réactives
human, mouse
Application
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
OTX015, ≥98% (HPLC),
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
BRD2, BD1, BD2 (65-459) GST tag human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Espèce(s)
human
BRD2 (339-459) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Espèce(s)
human
BRD2 (65-187) GST tag human, recombinant, expressed in E. coli, ≥81% (SDS-PAGE),
Espèce(s)
human
BRD2 (65-187) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Espèce(s)
human
BRD2 (339-459) GST tag human, recombinant, expressed in E. coli, ≥86% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Brd2,
Espèce(s)
mouse
MISSION® esiRNA, targeting human BRD2,
Espèce(s)
human