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APOB

apolipoprotein B

Synonymes:
FLDB, LDLCQ4
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(338) Summary: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
  • Mouse(238055) apolipoprotein B
  • Rat(54225) apolipoprotein B
  • domestic guinea pig(100725937) apolipoprotein B
  • Domestic Rabbit(100009101) apolipoprotein B (including Ag(x) antigen)
  • Horse(100071824) apolipoprotein B (including Ag(x) antigen)
  • cow(494004) apolipoprotein B
  • sheep(101107590) apolipoprotein B (including Ag(x) antigen)
  • chicken(396535) apolipoprotein B (including Ag(x) antigen)
  • domestic cat(101098863) apolipoprotein B (including Ag(x) antigen)
  • dog(475680) apolipoprotein B (including Ag(x) antigen)
  • naked mole-rat(101703081) apolipoprotein B

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ELISA

Référence du produit
Description
Espèce(s)
Human APOB / Apolipoprotein ELISA Kit, ,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Apolipoprotein B Antibody, serum, Chemicon®,
Espèces réactives
human
Application
immunoprecipitation (IP)
western blot
Anti-ApoB Antibody, clone MB47 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
canine, guinea pig, human, porcine, rabbit
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-ApoB Antibody, clone 2G11, clone 2G11, from mouse,
Espèces réactives
hamster, mouse, rat
Application
ELISA
western blot
Anti-APOB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-APOB antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry

western blot

Proteins

Référence du produit
Description
Espèce(s)
Apolipoprotein B from human plasma, ≥95%, lyophilized powder,
Espèce(s)
human
Apolipoprotein B from human plasma, ≥95% (SDS-PAGE),
Espèce(s)
human
Apolipoprotein B, human, ,
Espèce(s)
human
Lipoprotein, high density from human plasma, ≥95% (SDS-PAGE), solution,
Espèce(s)
human
Lipoprotein, low density from human plasma, ≥95% (SDS-PAGE), solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human APOB,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Apob,
Espèce(s)
mouse