ADRA2A
adrenoceptor alpha 2A
Synonymes:
ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32
Espèce(s):
Human ADRA2A (150), Mouse Adra2a (11551), Rat Adra2a (25083), domestic guinea pig Adra2a (100135475), chicken ADRA2A (428980), sheep ADRA2A (100170317), Domestic Rabbit ADRA2A (100009424), Zebrafish adra2a (266750), dog ADRA2A (486888), domestic cat ADRA2A (664736) ...Plus
ID UniProtKB:
ID du gène:
- Human(150) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
- Mouse(11551) adrenergic receptor, alpha 2a
- Rat(25083) adrenoceptor alpha 2A
- domestic guinea pig(100135475) adrenergic receptor, alpha 2a
- chicken(428980) adrenergic, alpha-2A-, receptor
- sheep(100170317) adrenoceptor alpha 2A
- Domestic Rabbit(100009424) adrenoceptor alpha 2A
- Zebrafish(266750) adrenergic, alpha-2A-, receptor
- dog(486888) adrenoceptor alpha 2A
- domestic cat(664736) adrenoceptor alpha 2A
- sheep(101117291) adrenoceptor alpha 2A
- naked mole-rat(101723298) adrenoceptor alpha 2A
- cow(282135) adrenergic, alpha-2A-, receptor
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Small Molecule - Agonist
Référence du produit
Description
Espèce(s)
Guanfacine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Small Molecule - Antagonist
Référence du produit
Description
Espèce(s)
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-Adrenergic Receptor α-2A antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-ADRA2A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
canine, human, mouse, rat
Application
ELISA
immunocytochemistry
immunofluorescence
immunocytochemistry
immunofluorescence
Anti-ADRA2A antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunofluorescence
immunofluorescence
Anti-α2A Adrenergic Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, pig, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Blocker
Small Molecule - Mixed Agonist/Antagonist
Proteins
Référence du produit
Description
Espèce(s)
ChemiSCREEN Human α2A Adrenergic Receptor Membrane Preparation, Human alpha2A GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Espèce(s)
human