ACTN1
actinin, alpha 1
Synonymes:
BDPLT15
Espèce(s):
Human ACTN1 (87), Mouse Actn1 (109711), Rat Actn1 (81634), Domestic Rabbit ACTN1 (100341378), Zebrafish actn1 (560400), naked mole-rat Actn1 (101711839), domestic guinea pig Actn1 (100721342), cow ACTN1 (524770), chicken ACTN1 (373918), domestic cat ACTN1 (101097986) ...Plus
ID UniProtKB:
ID du gène:
- Human(87) Summary: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(109711) actinin, alpha 1
- Rat(81634) actinin, alpha 1
- Domestic Rabbit(100341378) actinin, alpha 1
- Zebrafish(560400) actinin, alpha 1
- naked mole-rat(101711839) actinin, alpha 1
- domestic guinea pig(100721342) actinin, alpha 1
- cow(524770) actinin, alpha 1
- chicken(373918) actinin, alpha 1
- domestic cat(101097986) actinin, alpha 1
- dog(480369) actinin, alpha 1
- sheep(101122194) actinin, alpha 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-α Actinin antibody, Mouse monoclonal, clone BM-75.2, purified from hybridoma cell culture,
Espèces réactives
human
Application
immunofluorescence
western blot
western blot
Anti-α-Actinin Antibody, clone AT6/172, clone AT6/172, Upstate®, from mouse,
Espèces réactives
human, mouse, rabbit
Application
immunocytochemistry
western blot
western blot
Anti-ACTN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-α Actinin Antibody, clone AT6/172 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-α-Actinin-1 Antibody, clone 2C17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Référence du produit
Description
Espèce(s)
α-Actinin from chicken gizzard, ~80% α-actinin basis (SDS-PAGE), ammonium sulfate suspension,
Espèce(s)
mouse, chicken, rat, human