KitAlysis™ Photocatalysis Reaction Screening Kit

Materials Included in your Kitalysis™ High-Throughput Photocatalysis Reaction Screening Kit

• 22 (11 x 2) pre-weighed bases in glass vials loaded with stir bars, topped with cap mat.
• 4 empty reaction vials with lids (to make stock solutions)

The screening sets come pre-loaded with 30 µmol of base in each vial according to the following design.

Product No.	Description	Vial
333190	Bismuth(III) sulfide	B3
793221	9-Mesityl-10-phenylacridinium tetrafluoroborate	B4
900421	9-Mesityl-3,6-di-tert-butyl-10-phenylacridinium tetrafluoroborate	B5
46955	Fluorescein	B6
224758	Ru(bpy)3Cl2·6H2O	C1
804215	[Ir{dFCF3ppy}2(bpy)]PF6	C2
232017	Tetrachloro-1,4-benzoquinone	C3
900693	9-Mesityl-1,3,6,8-tetramethoxy-10-phenylacridin-10-ium tetrafluoroborate	C5
272345	2,4,6-Triphenylpyrylium tetrafluoroborate	C6
343714	Ru(phen)3Cl2·xH2O	D1
688096	Ir(ppy)3	D2
D60400	2,3-Dichloro-5,6-dicyano-p-benzoquinone	D3
794171	9-Mesityl-10-methylacridinium tetrafluoroborate	D4
900694	10-(3,5-Dimethoxyphenyl)-9-mesityl-1,3,6,8-tetramethoxyacridin-10-ium tetrafluoroborate	D5
900692	2,4,6-Tris(4-methoxyphenyl)pyrylium tetrafluoroborate	D6

Product No.	Description	Vial
747777	[Ru(bpz)3][PF6]2	A1
747769	[Ir(dtbbpy)(ppy)2]PF6	A2
637017	Bismuth(III) oxid	A3
318337	Acridine Orange HCl hydrate	A4
P2508	Proflavine hemisulfate salt hydrat	A5
459852	9,10-Anthracenedicarbonitrile	A6
747785	[Ru(bpm)3][Cl]2	B1

Ampule Boxes:

• 4 empty 4 mL reaction vials
• 2 (2 mL) ampule each of the following: ethylene glycol, DIPEA
• 4 (2 mL) ampule each of the following: toluene, DMA, THF, 1-butanol. MEOH, MECN

Internal Standard:

• Biphenyl (30mg). To be added to the reaction during the work-up. Recipe for the work-up with the internal standard can be found within the step-by-step guide

KitAlysis™ 24-well Reaction Block Replacement Films-2EA

• Pack of 2 enables a new film to be used with each kit ensuring a tight, cross-contaminate-free seal every time.

Stir Bars-8 individually packed

• Fit perfectly into supplied vials to ensure proper stirring of substrate mixtures.

Kit Design

The PhotoKitAlysis Reaction Kit was designed to provide the best possible chance of finding good reaction conditions for cross-coupling reactions:

• pre-weighed base or base solution (provided)
• 10–20 mmol coupling partner (user supplied)
• 10 mmol aryl halide substrate (user supplied)
• Catalysts (user supplied).
• 6 solvents (toluene, DMA. THJF, n-butanol, MeOH, MeCN) (provided)

Multiple tools have been created to ensure your success with kit set up. Start with the more detailed guide to ensure you are comfortable with all of the steps before using the quick guides on the excel worksheet. Remember that while the technique is new, it is still organic chemistry and so the steps will seem easy once you try just one kit. It is just a new way of approaching something you are already very good at.

Detailed Set-Up User Guide:

Designed for the first time user and should be read completely before getting started. Best if used in conjunction with the video as not all steps are outlined in the video in great detail. This guide includes trouble-shooting tips, how-to’s for the Labware, and work-up recipes with procedures. Everything you need to set up a kit with confidence every time.

Excel Sheet:

Each sheet is designed to be used with the specific experimental design chosen by you depending upon the attributes of your substrates. The downloadable excel files are specific to the kit being run and can be found within each Step-by-Step User Guide.

They have the following features:

• Calculations for substrate recipes depending upon the molecular weight of your substrates
• Quick directions for the more avid user
• Print button to allow you to take recipe to the lab
• Contain all info such that they can be can be saved as a pdf and appended to ELN for experimental information