SupraSolv^® GC Solvent Specifications

Our GC solvent qualities are ideal for all gas chromatography applications. These solvents are specially developed and tested for ECD, FID and MS detection to ensure a maximum signal-to-noise ratio in the largest specified retention time range. Our solvents for headspace gas chromatography are developed specifically for the analysis of residual solvents in drug substances, excipients, and drug products according to Ph. Eur. and USP. High purity is provided by specially designed production processes for accurate, reliable and reproducible analytical results.

SupraSolv^® GC Solvents Specifications

SupraSolv® solvents	SupraSolv® Headspace for analysis of residual solvents	SupraSolv® hypergrade for organic trace analysis	SupraSolv® for GC-ECD/FID	SupraSolv® for GC-MS
Suitability Tested	GC Headspace technique	Electron capture detector, flame ionization detector and mass spectroscopy	Electron capture detector and flame ionization detector	GC-MS/MS
Descriptions	Free from contaminants could possibly interfere with GC analysis by coeluting with peaks of interest in the sample	Narrow specification, the highest purity, and larger retention time range; low boiling substances can be reliably detected; the permissible concentration of interference signals within the retention time range is lower	Meet EPA Method 508 and the stringent demands of capillary gas chromatography; glass-distilled solvents resulting in exceptional quality and low residue levels	Undergo rigorous purification procedures and assure high chemical purity; lowest impurity profile and minimal signal-to-noise ratio in specification
Specification	Every residual solvent of class 1 acc. CH ≤ 1 µg/g Every residual solvent of class 2 acc. CH ≤ 10 µg/g Every residual solvent of class 3 acc. CH ≤ 50 µg/g	≤ 1 ng/mL compared to Tetrachloromethane GC-ECD ≤ 2 pg/mL compared to Lindane GC-ECD ≤ 2 ng/mL compared to n-Tetradecane GC-FID ≤ 2 ng/mL compared to n-Tetradecane GC-MS	3 pg/mL compared to Lindane GC-ECD ≤ 3 ng/mL compared to n-Tetradecane GC-FID	≤ 3 ng/mL compared to n-Tetradecane GC-MS
Benefits	Extremely high purity resulting in a very low baseline Microfiltered (0.2 μm) Packaged under inert gas for longer shelf life Meet USP, Ph. Eur. and ICH guidelines	Extremely low residual impurities Multi-purpose grade	Very high purity Improves column lifetime due to extremely low content of non-volatile matter low residue levels	Very high purity Improves column lifetime due to extremely low content of non-volatile matter
Applications	Residual solvents analysis in drug substances and products acc. Ph Eur & USP	Pesticide analysis Organic residue analysis	Volatile halogenated hydrocarbons in water Polychlorinated biphenyls (PCB) in water Detection of Acrylamide in food BTX analysis (Benzene, Toluene, Xylene) detection Hydrocarbon-oil-index in water Determination of emissions in car cockpit materials	Analysis of Dioxins and Furans (PCDD/PCDF) Analysis of polycyclic aromatic hydrocarbons Pesticide analysis acc. QuEChERS Determination of phthalates in plastics

SupraSolv^® solvents for gas chromatography ECD and FID

Solvent	Available Pack Sizes	Product Number
Acetone	1 L GL ,2.5 L GL ,4 L GL ,30 L ST	100012
Acetonitrile	1L GL ,2.5L GL	100017
tert-Butyl methyl ether	1 L GL ,2.5 L GL	101995
Chloroform, stabilized	1 L GL ,2.5 L GL	102432
Cyclohexane	1 L GL ,2.5 L GL ,4 L GL ,10 L ST	102817
Dichloromethane, stabilized	1 L GL ,2.5 L GL ,4 L GL ,10 L ST	106054
Diethyl ether, stabilized	1 L GL ,2.5 L GL ,4 L GL	100931
N,N-Dimethylformamide	1 L GL ,2.5 L GL	110983
Ethanol	1 L GL ,2.5 L GL	102371
Ethyl acetate	1 L GL ,2.5 L GL ,4 L GL ,10 L ST,30 L ST	110972
n-Hexane	1 L GL ,2.5 L GL ,4 L GL ,10 L ST,30 L ST	104371
Isohexane	2.5 L GL	104340
Isooctane	1 L GL ,2.5 L GL	115440
Methanol	1 L GL ,2.5 L GL,4 L GL	106011
n-Pentane	1 L GL ,2.5 L GL	100882
Petroleum benzine (40 - 60 °C)	1 L GL ,2.5 L GL ,4 L GL ,10 L ST,30 L ST	101772
2-Propanol	1 L GL ,2.5 L GL	100998
Toluene	1 L GL ,2.5 L GL ,4 L GL	108389
Water	1 L GL ,2.5 L GL	102699

GL = glass bottle I ST = stainless steel barrel I * = sum of hexane isomers + methyl cyclopentane (GC) ≥ 99.8 %
GC-ECD (retention range 1,2,4-Trichlorobenzene to Decachlorobiphenyle individual signals (Lindane standard)) :, 3 pg/mL
GC-FID (retention range n-Undecane to n-Tetracontane individual signals (n-Tetradecane standard)) :, 3 ng/mL

SupraSolv^® solvents for gas chromatography MS

Solvent	Available Pack Sizes	Product Number
Acetone	1L GL, 2.5L GL	100658
Acetonitrile	1L GL, 2.5L GL	100665
Cyclohexane	1L GL, 2.5L GL	100667
Dichloromethane, stabilized	1L GL, 2.5L GL	100668
Ethyl acetate	1L GL, 2.5L GL	100789
n-Hexane	1L GL, 2.5L GL	100795
Methanol	1L GL, 2.5L GL	100837
Toluene	1L GL, 2.5L GL	100849
Water	1L GL, 2.5L GL	103702
Water, ACS reagent, for ultratrace analysis	1L GL	14211
1-Methyl-2-pyrrolidinone	1L GL	43729
Methyl pivalate	1L GL	52596

GL = glass bottle I * = sum of hexane isomers + methyl cyclopentane (GC) ≥ 99.8 %
GC-MS (retention range n-Undecane to n-Tetracontane; scanning area 30 - 600 amu individual signals (n-Tetradecane standard)) ≤ 3 ng/mL

SupraSolv^® headspace for the analysis of residual solvents according to ICH, Ph Eur and USP

Solvent	Available Pack Sizes	Product Number
1-Methyl-2-pyrrolidone	0.5L GL, 1L GL, 2.5L GL	102497
Benzylalcohol	1L GL, 2.5L GL	102695
N,N-Dimethylacetamide	0.5L GL, 1L GL	100399
N,N-Dimethylformamide	1L GL, 2.5L GL	100202
Dimethyl sulfoxide	1L GL, 2.5L GL	101900
Water	1L GL, 2.5L GL	100577

GL = glass bottle
Every residual solvent of class 1 acc. CH ≤ 1 μg/g
Every residual solvent of class 2 acc. CH ≤ 10 μg/g
Every residual solvent of class 3 acc. CH ≤ 50 μg/g

SupraSolv^® hypergrade solvents for organic trace analysis

Solvent	Available Pack Sizes	Product Number
Dichloromethane	1L GL	106454
n-Hexane	1L GL, 2.5L GL	104369
n-Pentane	1L GL, 2.5L GL	107288
Petroleum benzine (40 - 60°C)	1L GL, 2.5L GL	116740

GL = glass bottle
* Sum of hexane isomers + methylcyclopentane (GC) > 99.9 %
GC-ECD (retention range Dichloromethane to 1,2,4-Trichlorobenzene individual signals (Tetrachloromethane standard)) ≤ 1 ng/mL
GC-ECD (retention range 1,2,4-Trichlorobenzene to Decachlorobiphenyle individual signals (Lindane standard)) ≤ 2 pg/mL
GC-FID (retention range n-Undecane to n-Tetracontane individual signals (n-Tetradecane standard)) ≤ 2 ng/mL
GC-MS (retention range n-Undecane to n-Tetracontane; scanning area 30 - 600 amu individual signals (n-Tetradecane standard) ≤ 2 ng/mL