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  • An efficient synthesis of nitroalkenes by alkene cross metathesis: facile access to small ring systems.

An efficient synthesis of nitroalkenes by alkene cross metathesis: facile access to small ring systems.

Organic letters (2007-06-07)
Graham P Marsh, Philip J Parsons, Clive McCarthy, Xavier G Corniquet
ABSTRACT

A synthesis of highly functionalized nitroalkenes is reported that utilizes a cross metathesis (CM) reaction between simple aliphatic nitro compounds and a range of substituted alkenes. This chemistry offers a simple and attractive route to nitroalkenes that would otherwise be difficult to prepare, and that have a very useful application as precursors to a variety of heterocyclic entities.

MATERIALS
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Product Description

Sigma-Aldrich
4-Bromostyrene, contains 0.05% 3,5-di-tert-butylcatechol as inhibitor, 97%