- Molecular iodine-catalyzed facile procedure for N-Boc protection of amines.
Molecular iodine-catalyzed facile procedure for N-Boc protection of amines.
The Journal of organic chemistry (2006-10-10)
Ravi Varala, Sreelatha Nuvula, Srinivas R Adapa
PMID17025327
ABSTRACT
An efficient and practical protocol for the protection of various structurally and electronically divergent aryl and aliphatic amines using (Boc)2O in the presence of a catalytic amount of molecular iodine (10 mol %) under solvent-free conditions at ambient temperature is presented.
MATERIALS