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  • Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity.

Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity.

Bioorganic & medicinal chemistry (2004-01-16)
John W Clader, William Billard, Herbert Binch, Lian-Yong Chen, Gordon Crosby, Ruth A Duffy, Jennifer Ford, Joseph A Kozlowski, Jean E Lachowicz, Shengjian Li, Charles Liu, Stuart W McCombie, Susan Vice, Gowei Zhou, William J Greenlee
ABSTRACT

Anthranilamide analogues such as 23 are potent and highly selective muscarinic M2 antagonists that also show good oral bioavailability and in vivo activity.

MATERIALS
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Brand
Product Description

Sigma-Aldrich
1-Boc-4-piperidone, 98%