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  • Cantharidin biosynthesis in a blister beetle: inhibition by 6-fluoromevalonate causes chemical disarmament.

Cantharidin biosynthesis in a blister beetle: inhibition by 6-fluoromevalonate causes chemical disarmament.

Experientia (1986-07-15)
J E Carrel, J P Doom, J P McCormick
ABSTRACT

Biosynthesis of cantharidin in a blister beetle, Lytta polita, is effectively inhibited by 6-fluoromevalonate. Inhibition is attributed specifically to the fluorine substituent. Biochemical inhibition has not been demonstrated previously for an arthropod's defensive substance.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
6-Fluoromevalonate, ≥90% (GC), viscous liquid