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  • Effective treatment of tinea corporis due to Trichophyton mentagrophytes with combined isoconazole nitrate and diflucortolone valerate therapy.

Effective treatment of tinea corporis due to Trichophyton mentagrophytes with combined isoconazole nitrate and diflucortolone valerate therapy.

Mycoses (2013-04-19)
Viktor A Czaika
ABSTRACT

Trichophyton mentagrophytes is the dermatophyte species most commonly reported in cases of guinea pig-associated dermatophytosis (or guinea pig fungus) a condition that more often affects children than adults. In this case, a 13-year-old girl with recent direct contact with guinea pigs presented with a previously undertreated inflammatory skin lesion on the left side of her upper body, which was positive both for Trichophyton mentagrophytes and Staphylococcus epidermidis. The condition was subsequently diagnosed as tinea corporis due to Trichophyton mentagrophytes with concomitant bacterial infection and effectively treated with 2 weeks of twice-daily application of Travocort cream containing isoconazole nitrate 1% and diflucortolone valerate 0.1%. Visible improvement in the lesion was apparent after only 1 week of treatment.

MATERIALS
Product Number
Brand
Product Description

Supelco
(±)-Miconazole nitrate salt, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
(±)-Miconazole nitrate salt, imidazole antibiotic
Isoconazole, European Pharmacopoeia (EP) Reference Standard
Isoconazole nitrate, European Pharmacopoeia (EP) Reference Standard
Miconazole nitrate, European Pharmacopoeia (EP) Reference Standard