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  • Transdermal granisetron: a guide to its use in preventing nausea and vomiting induced by chemotherapy.

Transdermal granisetron: a guide to its use in preventing nausea and vomiting induced by chemotherapy.

CNS drugs (2012-07-28)
Gillian M Keating, Sean T Duggan, Monique P Curran
ABSTRACT

Transdermal granisetron (Sancuso®) is effective in the prevention of nausea and vomiting in patients with cancer who are receiving moderately or highly emetogenic chemotherapy for 3-5 days. Transdermal granisetron is noninferior to oral granisetron in this indication, and is generally well tolerated in this indication. Thus, transdermal granisetron provides a convenient option for the prevention of chemotherapy-induced nausea and vomiting, with the potential to improve patient compliance.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Granisetron hydrochloride, ≥98% (HPLC), solid
Granisetron hydrochloride, European Pharmacopoeia (EP) Reference Standard