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  • Flavin-photosensitized monomerization of dimethylthymine cyclobutane dimer in the presence of magnesium perchlorate.

Flavin-photosensitized monomerization of dimethylthymine cyclobutane dimer in the presence of magnesium perchlorate.

Photochemistry and photobiology (1993-11-01)
K Miyake, Y Masaki, I Miyamoto, S Yanagida, T Ohno, A Yoshimura, C Pac
ABSTRACT

We have investigated the photosensitized monomerization of the cis,syn-cyclobutane dimer of 1,3-dimethylthymine using riboflavin tetraacetate and a 5-deazaflavin derivative as photosensitizer. Although little monomerization of the dimer is induced by photoexcitation of the flavins in the absence of any additives, the flavins can function as an efficient photosensitizer in the presence of magnesium perchlorate. Mechanistic studies involving spectroscopic, quantum-yield and flash-photolysis measurements demonstrated that the photosensitized monomerization exclusively proceeds through electron transfer from the dimer to the triplet flavins complexed with Mg2+. The effects of magnesium perchlorate are compared with those on the chloranil-photosensitized monomerization and also with the effects of HClO4 on the flavin-photosensitized reaction.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Magnesium perchlorate, ACS reagent
Sigma-Aldrich
Magnesium perchlorate, puriss., free-flowing powder, ≥99.0% (calc. based on dry substance, KT)
Sigma-Aldrich
Magnesium perchlorate, puriss. p.a., drying agent, ACS reagent, ≥98.0% (calc. based on dry substance, KT)