Structure-activity effects in peptide self-assembly and gelation - Dendritic versus linear architectures.

Structure-activity effects in peptide self-assembly and gelation - Dendritic versus linear architectures.

Chemical communications (Cambridge, England) (2012-07-05)

Cecile A Lagadec, David K Smith

ABSTRACT

We demonstrate that linear-dendritic shape-isomerism can have an impact on the gelation potential of peptides based on lysine, but the architectural effects can be inverted depending on the choice of functional groups, with the nature of these protecting groups dominating the gelation ability.

MATERIALS

Product Number

Brand

Product Description

D56802

Sigma-Aldrich

1,2-Dichlorobenzene, ReagentPlus^®, 99%

270598

Sigma-Aldrich

1,2-Dichlorobenzene, suitable for HPLC, 99%

240664

Sigma-Aldrich

1,2-Dichlorobenzene, anhydrous, 99%

36707

Supelco

1,2-Dichlorobenzene, PESTANAL^®, analytical standard

612510

Sigma-Aldrich

1,2-Dichlorobenzene solution, NMR reference standard, 5% in acetone-d₆ (99.9 atom % D), NMR tube size 5 mm × 8 in.