- In Vitro Activity of Isavuconazole against Rasamsonia Species.
In Vitro Activity of Isavuconazole against Rasamsonia Species.
Antimicrobial agents and chemotherapy (2016-08-17)
J Steinmann, S Dittmer, J Houbraken, J Buer, P-M Rath
PMID27527087
ABSTRACT
The in vitro susceptibilities to the novel triazole isavuconazole and six other antifungal agents of a large collection of Rasamsonia isolates (n = 47) belonging to seven species were determined. Isavuconazole and voriconazole had no in vitro activity (MIC, >32 mg/liter) against isolates of the Rasamsonia argillacea species complex. The echinocandins were the most potent antifungal drugs against all of the isolates tested (minimum effective concentration, ≤0.19 mg/liter).
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