- A novel protein, Mpm1, of the mitochondria of the yeast Saccharomyces cerevisiae.
A novel protein, Mpm1, of the mitochondria of the yeast Saccharomyces cerevisiae.
Bioscience, biotechnology, and biochemistry (2002-01-17)
H Inadome, Y Noda, H Adachi, K Yoda
PMID11791739
ABSTRACT
A previously uncharacterized yeast protein, YJL066c, was discovered in the membrane fraction although it has no hydrophobic stretch. The protein was partly solubilized by Triton X-100 in an oligomeric form, while it was insoluble in alkali or salt. By immunofluorescent microscopy, its localization coincided with the mitochondria. We therefore propose it should be named Mpm1 (mitochondrial peculiar membrane protein 1).
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HDAC Assay Buffer, 5X, The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity & represses transcription when tethered to a promoter.