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60188

Sigma-Aldrich

Potassium dichromate

BioUltra, ≥99.5% (RT)

Synonym(s):

Potassium bichromate

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About This Item

Linear Formula:
K2Cr2O7
CAS Number:
7778-50-9
Molecular Weight:
294.18
EC Number:
231-906-6
MDL number:
MFCD00011367
UNSPSC Code:
12352200
PubChem Substance ID:
57651731

product line

BioUltra

Assay

≥99.5% (RT)

impurities

insoluble matter, passes filter test

loss

≤0.05% loss on drying, 110 °C

pH

3.5-5.0 (25 °C, 0.1 M in H2O)

mp

398 °C (lit.)

solubility

H2O: 0.1 M at 20 °C, clear, orange

anion traces

chloride (Cl-): ≤10 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤20 mg/kg
Cd: ≤10 mg/kg
Co: ≤20 mg/kg
Cu: ≤10 mg/kg
Fe: ≤20 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤20 mg/kg
Pb: ≤50 mg/kg
Sr: ≤50 mg/kg
Zn: ≤10 mg/kg

absorption

no transmittance (UV) in H2O at 0.1 M

SMILES string

[K+].[K+].[O-][Cr](=O)(=O)O[Cr]([O-])(=O)=O

InChI

1S/2Cr.2K.7O/q;;2*+1;;;;;;2*-1

InChI key

KMUONIBRACKNSN-UHFFFAOYSA-N

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Application

Potassium bichromate may be used to induce acute renal failure (ARF) that mimics occupational hazards. It may be used to study the mechanism and affects of chromium induced renal failure and rescue methodologies.

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Dam. 1 - Muta. 1B - Ox. Sol. 2 - Repr. 1B - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 1 Inhalation - STOT SE 3

Target Organs

Cardio-vascular system, Respiratory system

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Amrit Pal Singh et al.
Pharmacological reports : PR, 64(1), 31-44 (2012-05-15)
The animal models are pivotal for understanding the characteristics of acute renal failure (ARF) and development of effective therapy for its optimal management. Since the etiology for induction of renal failure is multifold, therefore, a large number of animal models
N Susa et al.
Archives of toxicology, 71(6), 345-350 (1997-01-01)
Incubation of primary cultures of rat hepatocytes with K2CR2O7 and deferoxamine (DFO), an iron chelator, resulted in a marked decrease in cellular levels of DNA single-strand breaks caused by K2Cr2O7. Cellular treatment with DFO also suppressed both dichromate-induced cytotoxicity--evaluated by
Peter A Siver et al.
American journal of botany, 102(6), 921-941 (2015-06-24)
Heterokont algae of the class Synurophyceae, characterized by distinctive siliceous scales that cover the surface of the cell, are ecologically important in inland waters, yet their evolutionary history remains enigmatic. We explore phylogenetic relationships within this group of algae relative
Fu-Jun Liu et al.
Toxicological sciences : an official journal of the Society of Toxicology, 110(2), 307-318 (2009-06-03)
Werner syndrome is a premature aging disorder characterized by cancer predisposition that is caused by loss of the Werner syndrome protein (WRN) helicase/exonuclease DNA repair protein. Hexavalent chromium is an environmental carcinogen and genotoxicant that is associated with respiratory cancers
Eduardo Molina-Jijón et al.
Toxicology, 291(1-3), 93-101 (2011-11-26)
Deferoxamine (DFO) is a recognized iron chelator which has been shown to exert nephroprotection in models of toxic nephropathies. In the present work the potential protective effects of DFO against Cr(VI)-induced nephrotoxicity and oxidant stress were evaluated. Rats were injected
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