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Key Documents

52495

Sigma-Aldrich

Hexadimethrine bromide

for protein sequence analysis, ≥94% (AT)

Synonym(s):

1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide, Polybrene

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352200
Pricing and availability is not currently available.

grade

for protein sequence analysis

Assay

≥94% (AT)

solubility

H2O: 0.1 g/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

2-8°C

InChI

1S/C10H24N2.C3H6Br2/c1-11(2)9-7-5-6-8-10-12(3)4;4-2-1-3-5/h5-10H2,1-4H3;1-3H2

InChI key

KZKAYEGOIJEWQB-UHFFFAOYSA-N

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Application

Facilitates automated sequencing of small peptides.[1] Used to coat glass microfiber sheets for protein blotting.[2]

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Pictograms

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Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J Vandekerckhove et al.
European journal of biochemistry, 152(1), 9-19 (1985-10-01)
A procedure has been developed which allows the immobilization on glass-fiber sheets coated with the polyquaternary amine, Polybrene, of proteins and protein fragments previously separated on sodium-dodecylsulfate-containing polyacrylamide gels. The transfer is carried out essentially as has been used for
Automated amino acid sequence of small peptides utilizing Polybrene.
D G Klapper et al.
Analytical biochemistry, 85(1), 126-131 (1978-03-01)
Kimberly A Brown et al.
Journal of cellular biochemistry, 105(2), 596-611 (2008-08-30)
Transforming growth factor-beta 1 (TGF-beta1) is an important growth inhibitor of epithelial cells and insensitivity to this cytokine results in uncontrolled cell proliferation and can contribute to tumorigenesis. TGF-beta1 signals through the TGF-beta type I and type II receptors, and
[Chemiluminescence of peritoneal macrophages activated by non-natural polyelectrolytes].
L G Korkina et al.
Doklady Akademii nauk SSSR, 282(1), 206-209 (1985-05-01)
Hua Yang et al.
Investigative ophthalmology & visual science, 51(1), 28-34 (2009-08-08)
Pigment epithelium-derived factor (PEDF) is known to be an angiogenesis suppressor and to have antitumor effects. This study investigates whether constitutive overexpression of PEDF inhibits the growth and hepatic micrometastasis of ocular melanoma. Real-time RT-PCR was used to detect endogenous

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