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09170

Sigma-Aldrich

4-Aminophenol hydrochloride

for photographic purposes, ≥99.0% (AT)

Synonym(s):

4-Hydroxyaniline hydrochloride

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About This Item

Linear Formula:
H2NC6H4OH · HCl
CAS Number:
51-78-5
Molecular Weight:
145.59
Beilstein:
3911747
EC Number:
200-122-6
MDL number:
MFCD00012996
UNSPSC Code:
12352107
PubChem Substance ID:
329748716
NACRES:
NA.25

grade

for photographic purposes

Quality Level

200

Assay

≥99.0% (AT)

mp

300-305 °C (dec.) (lit.)
300-305 °C (dec.)

SMILES string

Cl[H].Nc1ccc(O)cc1

InChI

1S/C6H7NO.ClH/c7-5-1-3-6(8)4-2-5;/h1-4,8H,7H2;1H

InChI key

RVGOBWDGAVAVPJ-UHFFFAOYSA-N

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Application

4-Aminophenol hydrochloride can be used to study cell biology, bioactive small molecules, chemical synthesis, organic building blocks, oxygen compounds and phenols. 4-Aminophenol hydrochloride has been used to study ferrihemoglobin and kidney lesions in rats.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1 - STOT RE 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBF4441V
BCBF4840V
1363519V
1369519V
049196/1

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M Kiese et al.
Archives of toxicology, 34(4), 337-340 (1975-12-18)
4-Dimethylaminophenol hydrochloride (DMAP), 20mg/kg i.v., was found to oxidize in rats as much as 50% of the hemoglobin to ferrihemoglobin but did not cause kidney lesions. 4-Aminophenol hydrochloride, 400 mg/kg i.v., oxidized only 25% of the hemoglobin and produced large
Annette John-Baptiste et al.
International journal of toxicology, 31(6), 529-536 (2012-11-03)
Kidney injury biomarkers have been utilized by pharmaceutical companies as a means to assess the potential of candidate drugs to induce nephrotoxicity. Multiple platforms and assay methods exist, but the comparison of these methods has not been described. Millipore's Kidney
Yanpeng Xue et al.
Journal of colloid and interface science, 379(1), 89-93 (2012-05-23)
In this study, a facile one-step redox polymerization method for the preparation of highly dispersed palladium (Pd)/polypyrrole (PPy) nanocapsules has been demonstrated. During the polymerizaion process, the formation of RB-PdCl(4)(2-) complex via an electrostatic interaction plays a key role for
Rosivaldo S Borges et al.
Chemical biology & drug design, 81(3), 414-419 (2013-02-15)
This theoretical and experimental study describes the design and evaluation of the free-radical scavenging effect for the molecular association of 4-aminophenol and salicylate derivatives. For this purpose, we employed theoretical methods for the selection of antioxidant drugs and the rapid
Hyeok-Jin Ko et al.
Biotechnology letters, 34(4), 677-682 (2011-12-02)
Aryl acylamidase (EC 3.5.1.13, AAA) acts on the amide bond between aryl and acyl groups. Whole cells of Escherichia coli overexpressing a novel bacterial AAA synthesized p-acetaminophenol (p-AAP) from p-aminophenol (p-AP, aryl compound) and acetate (acyl donor). Optimum conditions were
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