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480100

Sigma-Aldrich

Neomycin Sulfate, γ-Irradiated, Tissue Culture Grade - CAS 1405-10-3 - Calbiochem

Sterilized by γ-irradiation. An aminoglycoside antibiotic that inhibits translation by binding to the 30S ribosomal subunit. Potency (anhydrous): ≥600 µg/mg.

Synonym(s):

Neomycin Sulfate, γ-Irradiated, Tissue Culture Grade - CAS 1405-10-3 - Calbiochem

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About This Item

Empirical Formula (Hill Notation):
C23H46N6O13 · 3H2SO4
CAS Number:
Molecular Weight:
908.88
UNSPSC Code:
12352200

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

color

off-white to yellow

solubility

water: 10 mg/mL

shipped in

ambient

storage temp.

−20°C

InChI

1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22?,23+;/m1./s1

InChI key

OIXVKQDWLFHVGR-GQTDVWSESA-N

General description

Potency (anhydrous): ≥600 µg/mg.
Sterilized by γ-irradiation. Aminoglycoside antibiotic that inhibits translation by binding to the small subunit of prokaryotic ribosomes.
Sterilized by γ-irradiation. An aminoglycoside antibiotic that inhibits translation by binding to the 30S ribosomal subunit.

Biochem/physiol Actions

Primary Target
Translation by binding to the small subunit of prokaryotic ribosomes. Potency (anhydrous): ≥600 µg/mg.

Warning

Toxicity: Carcinogenic / Teratogenic (D)

Reconstitution

Reconstitute in 20 ml of sterile deionized water to obtain a 10 mg/ml solution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Articles

Antibiotic kill curve is a dose response experiment in which mammalian cells are subjected to increasing amounts of selection antibiotic

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