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biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... STAT5B(6777)
Immunogen
amino acids 774-787 of human STAT5B (CGRPMDSQWIPHAQS)
Application
Anti-STAT5B Antibody is a Rabbit Polyclonal Antibody for detection of STAT5B also known as signal transducer & activator of transcription 5B & has been tested in WB.
Quality
routinely evaluated by immunoblot on mouse 3T3/A31 or human A431 cell lysates
Target description
90-92kDa
Physical form
Format: Purified
Analysis Note
Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Possible involvement of truncated signal transducer and activator of transcription-5 in the GH pattern-dependent regulation of CYP2C12 gene expression in rat liver.
Hanna Helander, Jan-Ake Gustafsson, Agneta Mode
Molecular Endocrinology null
J X Lin et al.
The Journal of biological chemistry, 271(18), 10738-10744 (1996-05-03)
We have isolated a second human Stat5 cDNA, Stat5B, and demonstrated that the genes encoding both Stat5A and Stat5B are located at chromosome 17q11.2. Both genes were constitutively transcribed in peripheral blood lymphocytes. By using specific antisera, we demonstrated that
M Girardot et al.
Oncogene, 34(10), 1323-1332 (2014-04-01)
STAT (Signal Transducer and Activator of Transcription) transcription factors are constitutively activated in most hematopoietic cancers. We previously identified a target gene, LPP/miR-28 (LIM domain containing preferred translocation partner in lipoma), induced by constitutive activation of STAT5, but not by
Benjamin Millot et al.
The Biochemical journal, 372(Pt 1), 41-52 (2003-02-13)
The upstream regulatory regions of the mouse and rabbit whey acidic protein (WAP) genes have been used extensively to target the efficient expression of foreign genes into the mammary gland of transgenic animals. Therefore both regions have been studied to
Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway.
Ghosh, P; Buchholz, MA; Yano, S; Taub, D; Longo, DL
Blood null
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