Z-011

Zidovudine solution

1.0 mg/mL in methanol, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₀H₁₃N₅O₄
• CAS Number: 30516-87-1
• Molecular Weight: 267.24
• MDL number: MFCD25542524
• UNSPSC Code: 41116107
• PubChem Substance ID: 329831595
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• format: single component solution
• storage temp.: −20°C
• SMILES string: CC(C(NC1=O)=O)=CN1[C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2
• InChI: 1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7-,8-/m1/s1
• InChI key: HBOMLICNUCNMMY-BWZBUEFSSA-N

Description

General description

Zidovudine, also known as azidothymidine (AZT), is a nucleoside analog reverse-transcriptase inhibitor (NRTI) antiretroviral used for the treatment of human immunodeficiency virus (HIV) infection. Therapeutic drug monitoring (TDM) of zidovudine may be requested to evaluate its toxicity, assess virological failure, guide dosing regimens, or investigate drug-drug interactions. This Certified Spiking Solution^® is suitable for use as starting material in the preparation of calibrators, controls, or linearity standards for a variety of LC-MS/MS or GC/MS zidovudine testing applications including TDM and clinical and diagnostic testing.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup